53 citations,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
37 citations,
June 2002 in “The Laryngoscope” Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.
[object Object] 36 citations,
May 2021 in “Nutrients” Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.
36 citations,
July 1977 in “The Journal of Pediatrics” Minoxidil helps lower blood pressure in kids with severe hypertension, but may cause temporary excessive hair growth.
31 citations,
January 2014 in “Journal of endocrinological investigation” Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
29 citations,
January 2019 in “Journal of the European Academy of Dermatology and Venereology” Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.
28 citations,
May 2012 in “Veterinary Dermatology” Different types of dog hair loss are linked to problems starting the hair growth phase and early hair cycle ending.
27 citations,
April 2020 in “Molecular Biology and Evolution” Ancient Chinese goats evolved cashmere-producing traits due to selective breeding, particularly in genes affecting hair growth.
23 citations,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
23 citations,
February 1979 in “Veterinary Clinics of North America: Small Animal Practice” Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
21 citations,
December 2012 in “European journal of pharmaceutics and biopharmaceutics” The nanoparticle-emulsion with polihexanide is more effective and lasts longer for skin antisepsis.
20 citations,
November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
19 citations,
October 2020 in “Biomedical Microdevices” Derma rollers show promise for skin improvement and drug delivery, but more research is needed on their safety and effectiveness.
17 citations,
June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
16 citations,
September 2018 in “Journal of Molecular Liquids” The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
16 citations,
September 2015 in “Journal of Ethnopharmacology” The document concludes that "Dictamnus" has a rich cultural history and potential as a herbal medicine, warranting more research into its effects and safety.
11 citations,
July 2014 in “Gene” The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
8 citations,
September 2022 in “Biointerface Research in Applied Chemistry” Quinoline alkaloids from Cinchona may help treat cancer, diabetes, fungal infections, and promote hair growth.
3 citations,
March 2017 in “Regulatory toxicology and pharmacology” Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
2 citations,
October 2015 in “Human Gene Therapy” The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
[object Object] Herbal remedies might help with hair loss but need more research for safety and effectiveness.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
January 2016 in “Elsevier eBooks” The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
January 2015 in “Dermatology” The document covers various dermatological treatments and conditions.
522 citations,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
187 citations,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.