522 citations,
January 2001 in “Cancer investigation” Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
282 citations,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
270 citations,
April 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.
189 citations,
March 2018 in “Human Reproduction Update” Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
124 citations,
January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
98 citations,
December 2003 in “The FASEB Journal” Thymosin β4 promotes hair growth by activating stem cells in hair follicles.
93 citations,
April 2012 in “International Journal of Cosmetic Science” Improving skin barrier and using antifungal treatments can help manage dandruff.
85 citations,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
76 citations,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
76 citations,
January 2017 in “World Journal of Stem Cells” Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
63 citations,
April 2018 in “Journal of the American Academy of Dermatology” Topical JAK inhibitors may help treat some skin conditions but need more research.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
47 citations,
May 2021 in “Polymers” Jojoba oil is highly valued for its diverse medicinal and industrial uses.
39 citations,
January 2019 in “Cells” Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.
35 citations,
August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
32 citations,
March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
31 citations,
April 2018 in “Royal Society open science” Sarcoptes scabiei infection causes significant health and behavior changes in wombats.
29 citations,
May 2018 in “Clinical Endocrinology” Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
25 citations,
July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
25 citations,
November 2008 in “Ophthalmic Plastic and Reconstructive Surgery” Radiofrequency and scalpel incisions have similar clinical outcomes for upper eyelid surgery.
24 citations,
October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
24 citations,
June 2011 in “Andrologia” Ganoderma lucidum may help treat enlarged prostate in rats.
22 citations,
January 2018 in “European urology focus” New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
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September 2014 in “Veterinary Dermatology” Low-level laser therapy seems to help dogs with noninflammatory alopecia grow hair back.
20 citations,
July 2006 in “Veterinary dermatology” Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.
19 citations,
March 1988 in “International Journal of Dermatology” Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.
18 citations,
April 2022 in “Frontiers in bioengineering and biotechnology” Gelatin microspheres with stem cells speed up healing in diabetic wounds.