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Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Manipulating cell cleanup processes could help treat hair loss.

Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

ADM scaffolds help skin heal by promoting a healing-type immune response.

Fetal hair follicles have melanocytes with melanosomes at different stages, which are broken down into pigment particles in keratinocytes.

Cathepsin L is essential for normal hair growth and development.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Minoxidil protects heart and improves recovery.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

The review says skin conditions with sterile pustules need more research for better treatments.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

The study found no common cause for a girl's crystalline cataract and uncombable hair, suggesting their co-occurrence might be coincidental.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

Charnoly bodies could be a marker for cell damage, and certain nutrients and proteins might prevent them, potentially helping with brain diseases and cancer.

Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.

FLCN helps control iron levels in cells.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.