research Perforin Expression by Cutaneous Gamma Delta T Cells
Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.
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research Polyphenols Rich Hibiscus Rosa Sinensis Linn. Petals Modulate Diabetic Stress Signaling Pathways in Streptozotocin-Induced Experimental Diabetic Rats
Hibiscus petals improved blood sugar and stress responses in diabetic rats.
research The Possible Implication of the S250C Variant of the Autoimmune Regulator Protein in a Patient with Autoimmunity and Immunodeficiency: In Silico Analysis Suggests a Molecular Pathogenic Mechanism for the Variant
The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.
research Hibiscus Rosa Sinensis Linn. Petals Modulate Glycogen Metabolism and Glucose Homeostasis Signaling Pathway in Streptozotocin-Induced Experimental Diabetes
Hibiscus petals helped control blood sugar and improve liver and pancreas health in diabetic rats.
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research Biotinidase Deficiency Characterized by Skin and Hair Findings
Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.
research Evolving Approaches to Profiling the Microbiome in Skin Disease
New technologies help us better understand how skin microbes affect skin diseases.
research Diverse Cellular Players Orchestrate Regeneration After Wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Rapid Preparation of a Noncultured Skin Cell Suspension That Promotes Wound Healing
Researchers developed a new method to quickly prepare skin cells that improve wound healing in rats.
research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model
Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.
research Syphilis: Today
Syphilis is becoming more common and remains a major health problem due to challenges in prevention and treatment.
research Mucosal TLR5 Activation Controls Healthspan and Longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Recent Advances in Single-Cell Engineered Live Biotherapeutic Products Research for Skin Repair and Disease Treatment
Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.
research Over-The-Counter Drugs Against Hair Loss
Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
research Flavonoids and Nod Factors: Importance in Legume-Microbe Interactions and Legume Improvement
Flavonoids and Nod factors are key for legume plant growth and could help in sustainable farming.
research Helminth Protein Enhances Wound Healing by Inhibiting Fibrosis and Promoting Tissue Regeneration
Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.
research The G-Protein Coupled Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis
GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
research Follicle Hormones
Follicle Stimulating Hormone is important for fertility.
research Acne Vulgaris
Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
research Cutaneous Signals of Immune System Disease
Skin issues can indicate immune system problems.
research Tradescantia-Based Test Systems for Evaluating Toxic Potential of Harmful Algal Blooms
Tradescantia plants can effectively test for the toxicity of harmful algae.
research Human Hair Shaft Proteomic Profiling: Individual Differences, Site Specificity, And Cuticle Analysis
Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.
research IL-3 Contributes to Development of Lupus Nephritis in MRL/Ipr Mice
IL-3 worsens lupus nephritis and blocking it improves kidney health.
research A WWP2–PTEN–KLF5 Signaling Axis Regulates Odontoblast Differentiation and Dentinogenesis in Mice
WWP2 is crucial for tooth development in mice.
research Stimulation of Hair Growth by Small Molecules That Activate Autophagy
Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
research Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Disruption of Tubular Flcn Expression as a Mouse Model for Renal Tumor Induction
Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.
research Suppression of Vitamin D Receptor and Induction of Retinoid X Receptor Alpha Expression During Squamous Differentiation of Cultured Keratinocytes
As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
research An Epistatic Effect of KRT25 on SP6 Is Involved in Curly Coat in Horses
The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
research Biomarkers of Selenium Status in Dogs
Urinary Se to creatinine ratio, serum Se, and glutathione peroxidase are effective early biomarkers for selenium status in dogs.