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The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Most American men experience hair loss by age 50, with limited effective treatments available and new options not expected soon.

Skin reactions to antidepressants are common but usually not serious and can be treated.

Cinnamon bark extract may help prevent weight loss and hair loss in breast cancer patients during chemotherapy and is safe to use.

A 27-year-old with APS-1 showed improvement in symptoms after treatment.

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.

Nested PCR can reliably identify fungal infections when traditional methods fail.

New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.

Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

IMA may indicate oxidative stress in skin and hair disorders, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Ringworm is a common, contagious fungal infection in dogs that can spread to humans and requires lengthy treatment.

Hair loss was found in 37.4% of surveyed rural high-school students in Eskisehir, Turkey, affecting their quality of life, especially in general health and mental well-being.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

The document discusses various challenging skin conditions and their treatments.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Procyanidin B-2 is safe to use on skin as a hair growth product.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.

PRFM may help treat hair loss, especially in mild cases.

The study suggests that people with rosacea are more likely to have chronic rhinosinusitis.

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Mood stabilizers can cause serious skin reactions; careful monitoring and immediate treatment are crucial.

Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.