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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Cancer patients treated with immune checkpoint inhibitors may develop alopecia, but some hair regrowth is possible with treatment.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.