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Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Hepatitis C virus can cause skin diseases and dermatologists play a crucial role in identifying these conditions.

Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.

Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

New treatments for hair loss show promise, but more development is needed, especially for tough cases.

The document concludes that proper diagnosis and evidence-based treatments are crucial for managing hair diseases, and psychological support for patients is important.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Certain nutrients can help keep skin healthy as we age.

The conclusion is that understanding the complex relationship between allergies, autoimmunity, and psychological factors is key to treating skin disorders with itching.

Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.

Licorice has many health benefits but more research is needed to fully understand them.

The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Athletes need effective management of skin disorders for their performance and well-being.

Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.