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      Overweight and Obesity in Children and Adolescents

      research Overweight and Obesity in Children and Adolescents

      356 citations , September 2014 in “Journal of Clinical Research in Pediatric Endocrinology”
      This article discusses the rising prevalence and serious implications of childhood obesity and reports no new experimental findings; the authors emphasize the importance of prevention and early intervention through comprehensive management programs.
      The Rotterdam Study: 2016 Objectives and Design Update

      research The Rotterdam Study: 2016 objectives and design update

      336 citations , August 2015 in “European Journal of Epidemiology”
      This article reviews the design and objectives of the Rotterdam Study, as well as summarizes major findings, without reporting new results.
      Severe Cutaneous Adverse Reactions to Drugs

      research Severe cutaneous adverse reactions to drugs

      273 citations , May 2017 in “The Lancet”
      This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
      The Rotterdam Study: 2014 Objectives and Design Update

      research The Rotterdam Study: 2014 objectives and design update

      266 citations , November 2013 in “European Journal of Epidemiology”
      This article outlines the rationale and design of the Rotterdam Study, summarizes its major findings, and updates its objectives and methods; it reports no new research results.
      Wnt Signaling and Injury Repair

      research Wnt Signaling and Injury Repair

      232 citations , June 2012 in “Cold Spring Harbor Perspectives in Biology”
      This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.
      Is COVID-19 Gender-Sensitive?

      research Is COVID-19 Gender-sensitive?

      228 citations , January 2021 in “Journal of Neuroimmune Pharmacology”
      This review explores possible reasons for why male COVID-19 patients experience more severe symptoms and higher fatality rates than female patients but provides no new clinical results.
      Eph Receptors and Ephrins: Therapeutic Opportunities

      research Eph Receptors and Ephrins: Therapeutic Opportunities

      222 citations , October 2014 in “Annual Review of Pharmacology and Toxicology”
      This review discusses the roles of Eph receptors and ephrins in various diseases, highlighting their potential as therapeutic targets, but it presents no new research findings.
      The Rotterdam Study: 2010 Objectives and Design Update

      research The Rotterdam Study: 2010 objectives and design update

      219 citations , September 2009 in “European journal of epidemiology”
      This article discusses the rationale, design, major findings, and updated objectives and methods of the ongoing Rotterdam Study on various diseases, without reporting new research results.
      Adverse Effects of Opioid Analgesic Drugs

      research ADVERSE EFFECTS OF OPIOID ANALGESIC DRUGS

      183 citations , January 1987 in “British Journal of Anaesthesia”
      This article discusses the long-standing use and safety of opioids in anaesthesia, noting that respiratory depression is a manageable side effect due to the availability of opioid antagonists.
      The PDGF/PDGFR Pathway as a Drug Target

      research The PDGF/PDGFR pathway as a drug target

      182 citations , November 2017 in “Molecular Aspects of Medicine”
      This review discusses various therapeutic strategies targeting platelet-derived growth factor signaling in diseases like cancer and atherosclerosis, and evaluates existing treatments without presenting new clinical data.
      Fetal Alcohol Syndrome: Current Status of Pathogenesis

      research Fetal Alcohol Syndrome: Current Status of Pathogenesis

      171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”
      The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
      Anthracycline Analogs: The Past, Present, And Future

      research Anthracycline analogs The past, present, and future

      168 citations , December 1986 in “Cancer Chemotherapy and Pharmacology”
      Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      S1 Guideline on Post-COVID/Long-COVID

      research S1-Leitlinie Post-COVID/Long-COVID

      156 citations , September 2021 in “Pneumologie”
      This review discusses the development of an interdisciplinary guideline on Post-COVID/Long-COVID symptoms, diagnostics, and therapies by the Deutsche Gesellschaft für Pneumologie, reporting no new results but highlighting ongoing updates based on emerging knowledge.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      Ichthyosis

      research Ichthyosis

      147 citations , January 2003 in “American journal of clinical dermatology”
      This review discusses various forms of ichthyosis, including genetic and acquired types, detailing their characteristics, causes, and potential management strategies, but reports no new clinical results.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations , March 2013 in “Circulation Research”
      This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
      Hormesis And Medicine: Biphasic Dose-Response Relationship

      research Hormesis and medicine

      127 citations , June 2008 in “British Journal of Clinical Pharmacology”
      This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.