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Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.

Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Anabolic steroid users may face higher risk of severe COVID-19.

The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Skin organoids from stem cells could better mimic real skin but face challenges.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Adding hyaluronic acid helps create larger artificial hair follicles in the lab.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.

Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.

Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.

Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.

Intestinal stem cells can help repair skin damage from radiation.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

CD8+ T cells play a key role in graft-versus-host disease in certain mice models.

Lactate production is important for activating hair growth stem cells.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.