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A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

SARS-CoV-2 might infect and multiply in skin tissue, possibly aiding in its transmission.

Spermidine may help reduce hair loss and deserves further testing as a treatment.

Runx3 helps determine hair shape.

Benign skin tumors need accurate diagnosis to ensure proper treatment.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

Markers help differentiate between apocrine and eccrine sweat glands to identify sweat gland tumors.

CT scans can find serious prostate cancer even when PSA levels are low.

Corin helps control salt and sweat release in sweat glands.

Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.

Stem cell self-renewal is complex and needs more research for full understanding.

Hair follicles are valuable for regenerative medicine and wound healing.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Cells with active Wnt signaling are less likely to turn into cancer when exposed to a cancer-causing gene.

Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.