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Integrin β1 is crucial for liver structure and function, preventing fibrosis.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

An imbalanced gut and lack of biotin can cause hair loss in mice.

The book is recommended for its new scientific information and balanced treatment options for hair loss in domestic animals.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Changing the diet of mice lacking the enzyme CBS can affect symptoms related to the genetic condition.

A 72-year-old man had severe fatigue, weight loss, and frequent loose stools.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.

Temporary hair loss can occur after brain AVM treatment but usually regrows in 8 weeks.

Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

Testosterone reduces key molecules needed for early pregnancy in rats.

The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Some people have a genetic variation that makes them less effective at breaking down drugs.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.