7 citations
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August 2021 in “Heliyon” This study suggests that the herbal formulation Phyllotex™ may promote hair growth in androgenetic alopecia by enhancing cell proliferation and reducing oxidative stress and TGF-β1 expression in vitro.
5 citations
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November 2024 in “Cells” This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.
4 citations
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January 2019 in “PubMed” This study found that women with female pattern hair loss had significant hormonal imbalances, specifically involving adrenal androgens, suggesting these may play a central role in the condition's development.
2 citations
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January 2024 in “IEEE Access” This study introduces AlopeciaDet, a novel feature fusion technique, using camera images to detect Alopecia Areata with 99.45% accuracy, outperforming existing methods by leveraging CRSHOG and ResNet-50 features.
March 2026 in “Pharmaceutics” This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.
January 2026 in “Dermatologic Therapy” In this review, BTXA treatment was reported to effectively increase hair density and improve follicle health in androgenetic alopecia patients by enhancing scalp blood flow and reducing inflammation, without significant adverse effects.
August 2025 in “International Journal of Molecular Sciences” This meta-analysis found that among topical OTC treatments for male androgenetic alopecia, minoxidil 5% applied twice daily was the most effective in increasing total hair density over 24 weeks.
March 2025 in “International Journal of Trichology” This study found that, in female patients with pattern hair loss, injections of adipose-derived stem cells increased hair density and thickness, reduced perifollicular inflammation, and enhanced markers associated with hair cycle regeneration.
February 2025 in “Clinical & Experimental Dermatology and Therapies” In this randomized trial, oral supplementation with Serenoa repens, pumpkin seed extracts, and cysteine significantly improved the clinical effectiveness of topical 5% minoxidil lotion for treating androgenic alopecia in men and women compared to minoxidil alone, with both treatments being well tolerated.
December 2024 in “Archiv Euromedica” This review highlights that diagnosing cicatricial alopecia, a hair loss condition linked to several autoimmune diseases, requires trichoscopy and histopathological examination to differentiate it from similar conditions, with early diagnosis being crucial for effective management.
November 2024 in “BMC Research Notes” This study found that in men with androgenetic alopecia, the expression levels of genes SIRT3 and SIRT7 were reduced, while NFATC1 and PDL-1 were elevated, aligning with patterns seen in aging hair follicles, suggesting these genes' roles in AGA pathogenesis.
July 2023 in “International journal of trichology” In this randomized controlled trial, researchers found that Cellcurin therapy significantly increased hair density, terminal hair, and vellus hair counts in men and women with androgenetic alopecia, compared to minoxidil control, over 12 weeks.
April 2023 in “Nigerian Journal of Clinical Practice” In this study, androgenetic alopecia in Nigerians was associated with dyslipidemia, alcohol intake, and sedentary lifestyle, with severity linked to age, systolic blood pressure, and obesity.
January 2023 in “Springer eBooks” Most older adults experience pattern hair loss due to shrinking hair follicles, with men and women showing different balding patterns.
January 2023 in “Springer eBooks” Hair restoration surgery can effectively treat hair loss in women.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses the causes and recommended clinical investigations for postmenopausal hyperandrogenism, highlighting the role of androgen excess in symptoms like hirsutism and its association with metabolic disorders.
January 2021 in “Global Dermatology” This study involved selecting patients with specific types of alopecia for treatment but does not report clinical outcomes.
September 2023 in “International Journal of Trichology” In this study reviewing recent literature, researchers found limited high-quality evidence supporting the use of adipose-derived stem cells for androgenic alopecia and alopecia areata, suggesting a need for further randomized controlled trials to better assess their efficacy.
April 2021 in “International Journal of Research in Dermatology” This study found that treating male pattern androgenetic alopecia with a combination of topical minoxidil and finasteride resulted in better outcomes for hair growth and density compared to using minoxidil alone.
January 2018 in “Our Dermatology Online” This review summarizes the use of injectable dutasteride mesotherapy for androgenic alopecia and reports improved hair growth when combined with other substances, but highlights the need for further studies to establish long-term protocols.
January 2016 in “Hematology & Transfusion International Journal” This study reported that three months of platelet-rich plasma injections improved hair counts, thickness, root strength, and overall alopecia in patients with androgenic alopecia, with no major adverse effects.
June 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that psoriasis, acne, and androgenetic alopecia are associated with an atherogenic lipid profile, suggesting an increased risk of atherosclerosis and cardiovascular disease, especially among psoriasis patients.
119 citations
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May 2020 in “Journal of The American Academy of Dermatology” This study observed a high prevalence of androgenetic alopecia in patients hospitalized with severe COVID-19, with 79% of men and 42% of women affected, suggesting a potential link between androgen sensitivity and COVID-19 severity.
5 citations
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May 2023 in “Frontiers in Immunology” This review provides an overview of how advancing imaging technologies, such as tissue clearing and intravital microscopy, are enhancing our understanding of tumor architecture and interactions between cancer cells and the tumor microenvironment, aiding both fundamental cancer research and the development of therapies.
26 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.
26 citations
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December 2020 in “Photodermatology Photoimmunology & Photomedicine” This review discusses photobiomodulation as a potential treatment for hair loss, highlighting its safety and possible effectiveness but noting cost, protocol standardization, and expectation management as limitations; it reports no new clinical results.
13 citations
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June 2020 in “Plastic and reconstructive surgery. Global open” This study found that preserving hair grafts in platelet-rich plasma before implantation significantly improved hair density, graft uptake, and hair thickness compared to saline preservation in hair transplantation patients.
12 citations
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January 2020 in “Indian Dermatology Online Journal” This article discusses the causes, diagnosis, and treatment options for female pattern hair loss, emphasizing the role of topical minoxidil as a primary treatment, but provides no new clinical results.
5 citations
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October 2024 in “International Journal of Molecular Sciences” This study observed that piperonylic acid activated key signaling pathways in dermal papilla cells and increased hair growth markers, and a clinical trial showed users of a piperonylic acid formulation had more hair than those using a placebo, suggesting its potential for treating hair loss.
5 citations
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March 2022 in “Frontiers in Medicine” This review analyzed 17 recent clinical trials on platelet-rich plasma for androgenetic alopecia but reports no new clinical results; the authors seek a consensus on optimal PRP use.