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The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Vitamin D and calcium are important for skin stem cell function and wound healing.

Scientists made working hair follicles using stem cells, helping future hair loss treatments.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

Different types of skin cells play specific roles in development, healing, and cancer.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Improving the environment and cell interactions is key for creating human hair in the lab.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.

New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Vitamin D helps skin stem cells heal wounds by working with a key skin protein.

Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.

Beta-caryophyllene helps improve wound healing in mice, especially in females.