September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
June 2017 in “Journal of The American Academy of Dermatology” Women in Australia report different signs of facial aging compared to women in the US, UK, and Canada; men with Lichen planopilaris often have hormonal abnormalities and thyroid disease.
June 2017 in “Journal of The American Academy of Dermatology” Most men with lichen planopilaris had it confirmed by biopsy and often had thyroid issues, sexual dysfunction, or prostate cancer, hinting at a link with hormonal problems.
April 2017 in “Australasian Journal of Dermatology” Most patients with Lichen planopilaris improved with acitretin, but treatments often didn't work well; preventing infection in skin surgery is important, and bupivacaine might be a better anesthetic.
Lichen planopilaris and frontal fibrosing alopecia are likely the same disease with different clinical appearances.
July 2015 in “Journal of the Dermatology Nurses’ Association” A 66-year-old woman experienced hair loss due to Frontal Fibrosing Alopecia, a condition with no consistently effective treatment, but it usually stabilizes over time. More research is needed for better understanding and treatment options.
May 2015 in “Journal of The American Academy of Dermatology” Oral minoxidil improved male baldness, but had side effects; certain antibiotics effectively treated a rare scalp condition; hair transplants might trigger another scalp condition.
May 2015 in “Journal of The American Academy of Dermatology” Mycophenolate mofetil may improve symptoms and stop hair loss in Lichen planopilaris, but more research is needed.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
September 2013 in “Hair transplant forum international” The document says doctors should identify and treat Frontal fibrosing alopecia medically before considering surgery, as treatments often don't work well.
Different hair and nail conditions can indicate health issues and have specific treatments; accurate diagnosis is crucial before treatment.
April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
43 citations,
March 2009 in “Archives of dermatology” No treatment showed clear superiority for lichen planopilaris.
1 citations,
October 2023 in “Skin research and technology” LC-OCT is an effective new method for diagnosing classic lichen planopilaris.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Ixekizumab may be an effective first treatment for a rare skin condition causing hair loss.
220 citations,
June 2013 in “The Journal of Pathology” The study on lichen planopilaris (LPP) involved 42 adult patients and demonstrated that the disease was characterized by the collapse of immune privilege in the hair follicle's epithelial stem cell niche, specifically in the bulge area. This collapse was marked by increased expression of MHC class I and II molecules and a reduction in TGFβ2 and CD200 expression, leading to a Th1-biased cytotoxic T cell response. The findings suggested that interferon-γ (IFNγ) played a significant role in this process, indicating that LPP might be an autoimmune disease. The study proposed that protecting or restoring immune privilege in the bulge could be a therapeutic strategy for managing this form of cicatricial alopecia.
39 citations,
March 2008 in “British Journal of Dermatology” Etanercept may cause lichen planopilaris, so doctors should be cautious.
29 citations,
March 2016 in “Dermatologic therapy” Platelet-rich plasma may successfully treat lichen planopillaris, as shown by one patient's symptom regression.
10 citations,
May 2020 in “Dermatologic therapy” Tildrakizumab significantly improved recalcitrant lichen planopilaris and frontal fibrosing alopecia.
June 2024 in “International Journal of Dermatology” Upadacitinib may effectively treat resistant lichen planopilaris.
19 citations,
March 2011 in “The Journal of Dermatology” A child's rare skin disease was triggered by chickenpox.
September 2021 in “CRC Press eBooks” Fibrosing alopecia in a pattern distribution is a type of hair loss that may often be overlooked, especially in men.
9 citations,
September 2010 in “Dermatologic therapy” Combining cetirizine and topical steroids can effectively manage severe lichen planus pilaris.
16 citations,
January 2017 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Managing frontal fibrosing alopecia and lichen planus pigmentosus is challenging due to resistant hair loss and skin discoloration.
1 citations,
July 2020 in “Journal of cosmetic dermatology” A woman on immunosuppressants developed two rare scalp conditions, which improved with specific treatments.
15 citations,
April 2020 in “Journal of The American Academy of Dermatology” Oral minoxidil can increase or maintain hair thickness in most people with lichen planopilaris, with mild side effects.
January 2022 in “Дерматологія та венерологія” Frontal fibrosing alopecia causes hair loss along the frontal hairline, mainly in postmenopausal women, and needs better treatments.
April 2017 in “Australasian Journal of Dermatology” The session covered updates on skin treatments, including radiotherapy, imiquimod, acitretin, JAK inhibitors, and strategies for managing rosacea and preventing surgical infections.
November 2012 in “South African Family Practice” The article concludes that early treatment of alopecia is crucial to prevent permanent hair loss.