December 2025 in “Portuguese Journal of Dermatology and Venereology” In this study, researchers conducted a retrospective analysis of 16 cases of erosive palmoplantar lichen planus in North East India, finding a higher prevalence in pediatric and male patients, with common clinical features including plantar involvement and histopathological indicators such as basal cell degeneration.
June 2023 in “British journal of dermatology/British journal of dermatology, Supplement” This case report describes a rare instance of lichen planus preceding vitiligo in a 13-year-old boy, suggesting a non-coincidental association between the two conditions.
April 2016 in “Journal of the American Academy of Dermatology” Treatment improved some symptoms but not all.
August 2026 in “Anais Brasileiros de Dermatologia” This systematic review found that while hair transplantation in patients with lichen planopilaris may serve as a cosmetic option, there is a notable decline in graft survival rates after two years, and the data currently lacks prospective studies for stronger evidence.
June 2026 in “Dermatology” In this study, frontal fibrosing alopecia showed a higher cumulative remission rate compared to lichen planopilaris, despite similar timeframes and relapse rates between the two conditions.
January 2026 in “European Journal of Therapeutics” In this study, researchers reported that applying topical 7.5% dapsone led to a significant decline in lichen planopilaris activity within a month and a sustained two-year remission in a patient intolerant to other treatments, suggesting dapsone as a promising alternative for managing this condition.
November 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers engineered ventral skin organoids (vSkOs) with specific cellular compositions and signaling environments to generate human amnion-like tissues called Amnioids, offering new tools for studying human development and potential regenerative therapies.
July 2025 in “Case Reports in Dermatology” This case report highlights that early signs like pili torti may precede lichen planopilaris in some patients, emphasizing the importance of timely intervention to prevent permanent hair loss.
March 2025 in “JEADV Clinical Practice” In this retrospective chart review, researchers found that patients with scarring alopecia, including central centrifugal cicatricial alopecia, have a higher prevalence of various systemic comorbidities, such as vitamin D deficiency and metabolic syndrome, compared to the general US population.
July 2024 in “Skin Appendage Disorders” This review discusses the role of trichoscopy in diagnosing lichen planopilaris and reports no clinical results; the authors emphasize early recognition to potentially prevent permanent scarring.
March 2024 in “Journal of cosmetic dermatology” This study found that platelet-rich plasma may be more effective and satisfactory than topical clobetasol for treating lichen planopilaris over six months.
April 2022 in “Actas Dermo-Sifiliográficas” This article discusses the case of a 59-year-old woman with a history of progressive facial hyperpigmentation and explores potential connections between her condition and her family history, but reports no clinical findings.
September 2021 in “CRC Press eBooks” This review discusses fibrosing alopecia in a pattern distribution and highlights diagnostic features, but reports no new clinical results; the authors emphasize the value of trichoscopy and histology in diagnosis.
January 2005 in “The Chinese Journal of Dermatovenereology” In this study, sodium fluoride at certain concentrations increased the MDA levels in cultured human hair follicles, while 0.01 mmol/L sodium selenite reduced this effect at lower fluoride concentrations.
52 citations
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February 2006 in “Archives of Dermatology” This case report describes a 25-year-old woman with widespread lichen planus who did not respond to multiple systemic treatments, including antihistamines, hydroxychloroquine sulfate, and corticosteroids.
35 citations
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November 2019 in “Journal of the American Academy of Dermatology” This study reviewed 40 patients with scalp symptoms and identified a new variant of diffuse lichen planopilaris in 20 individuals, suggesting these conditions should be considered in similar cases.
28 citations
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December 2007 in “Archives of ophthalmology” This study found that lash ptosis was more common and severe in eyes with blepharoptosis, especially congenital, compared to normal eyes.
22 citations
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August 2020 in “Journal of the American Academy of Dermatology” Women with lichen planopilaris and frontal fibrosing alopecia often have other health issues like hypothyroidism and lupus.
19 citations
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July 2022 in “PNAS Nexus” This study identified a shared gene signature in scarring alopecia subtypes, with increased mast cell presence, suggesting similar treatment approaches may be effective across these hair loss disorders.
16 citations
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October 2014 in “Journal of the American Academy of Dermatology” This study found that oral retinoid therapy may provide clinical improvement in a small percentage of patients with treatment-resistant lichen planopilaris, although it is not commonly used as a first-line treatment.
9 citations
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September 2010 in “Dermatologic therapy” This study found that combined therapy with cetirizine and topical steroids stabilized inflammation in most patients with lichen planus pilaris, though one patient experienced cardiac arrhythmia.
6 citations
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December 2021 in “Journal of Clinical Medicine” This study introduced the Lichen Planus Activity and Damage Index (LiPADI), which effectively assesses the severity and progression of lichen planus, aligning well with other clinical indicators.
5 citations
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August 2001 in “International Journal of Dermatology” This case study reports a 20-year-old laborer's progressive hair loss with scalp and body lesions, diagnosed as lichen planopilaris, leading to scarring alopecia resembling male-pattern baldness.
5 citations
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November 2023 in “Journal of Investigative Dermatology” People with primary cicatricial alopecia have a higher risk of heart disease and stroke.
4 citations
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January 2021 in “Postępy Dermatologii i Alergologii” This study found that hydroxychloroquine significantly reduced disease activity in women with frontal fibrosing alopecia and lichen planopilaris, particularly benefitting patients after 12 months of treatment.
4 citations
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July 2024 in “European Archives of Oto-Rhino-Laryngology” This study found that platelet-rich plasma injections significantly improved olfactory function in patients with long-lasting postviral olfactory dysfunction, suggesting potential as a therapeutic strategy.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Clinical signs don't match inflammation levels in lichen planopilaris and frontal fibrosing alopecia.
2 citations
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July 2024 in “Biomedicines” This study found that, in male patients with patellar tendinopathy, bone marrow mesenchymal stromal cell treatment improved tendon regeneration, organization, strength, and pain relief more effectively than leukocyte-poor platelet-rich plasma over 12 months.
1 citations
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July 2022 in “PLOS ONE” This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.
May 2025 in “Australasian Journal of Dermatology” In this observational study, researchers reported a significant association between COVID-19 infection or vaccination and the development of new-onset lichen planus, suggesting these events, particularly infection, may act as triggers for the condition.