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5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.

Finasteride reduces prostate cancer risk but may increase high-grade tumors and has side effects; biopsy methods have similar outcomes; psychosocial factors affect sexual recovery post-surgery.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Rats had lasting erectile problems after stopping a certain medication.

Method can accurately measure five BPH drugs at once.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Improved finasteride formula allows slow, sustained release and better absorption for patients.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.