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Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Micro-needling effectively improves wrinkles, scars, and hair growth, but proper technique and safety are important.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Smoking harms skin health, causing slower wound healing, more wrinkles, and worsening some skin conditions, but may protect against certain others.

Micropigmentation is a widely accepted tattooing technique for hiding cosmetic issues and medical uses, with permanent results and few side effects, but risks infection if not done with sterile tools.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.

Different sports can cause specific skin conditions that need proper diagnosis and treatment.

Most pregnant women experience skin changes like darkening and stretch marks, and some may have skin conditions that usually get better after giving birth.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Bimatoprost is safe and effective for improving eyebrow hair.

Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Platelet-Rich Plasma (PRP) shows promise for treating various skin conditions, but more research is needed to standardize its use.