25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
7 citations,
October 2000 in “Allergo Journal” Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
1010 citations,
August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
November 2023 in “Klìtinna ta organna transplantologìâ” MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.
3 citations,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
47 citations,
April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
66 citations,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
42 citations,
July 2017 in “Molecular therapy” A form of vitamin E promotes hair growth by activating a specific skin pathway.
19 citations,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
30 citations,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
8 citations,
March 2017 in “Experimental Dermatology” Finasteride helps female-pattern hair loss.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
109 citations,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
9 citations,
January 2015 in “Current problems in dermatology” New hair transplant method allows for hair regrowth in the donor area and less scarring.
9 citations,
July 2007 in “Journal of Investigative Dermatology” Claudin expression changes help the skin respond to injury.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
August 2024 in “International Journal of Molecular Sciences” Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
5 citations,
April 2023 in “BMC Microbiology” Shampoo with heat-killed Lacticaseibacillus paracasei GMNL-653 improves scalp health and hair growth by changing scalp bacteria.
6 citations,
August 2020 in “Cell regeneration” Hair follicle stem cells are similar to bone marrow stem cells but are better for fat cell research.
56 citations,
January 2021 in “Clinical and Experimental Medicine” The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
41 citations,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
25 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
November 2023 in “Journal of cosmetic dermatology” Fat transplants using a patient's own fat can rejuvenate and repair tissues effectively.
161 citations,
August 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
85 citations,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.