320 citations,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
2 citations,
June 2023 in “Pharmaceutics” Nanofiber scaffolds help wounds heal by delivering drugs directly to the injury site.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
10 citations,
January 2011 in “Journal of Cutaneous and Aesthetic Surgery” Surgical methods for hair loss are less common than hair transplants but still useful, especially for scarring hair loss.
4 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.
85 citations,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
17 citations,
October 2002 in “Dermatologic Surgery” Successful surgical hair restoration requires careful planning, precise execution, and proper aftercare, using techniques like follicular unit transplantation and correct hair angling for best cosmetic results.
8 citations,
January 2015 in “Journal of Cutaneous Medicine and Surgery” Hair restoration techniques have improved but still rely on limited donor hair, with new methods like cloning and gene therapy being explored.
5 citations,
February 2010 in “Facial Plastic Surgery Clinics of North America” The document concludes that understanding hair loss and considering medical treatments like minoxidil and finasteride before surgery is important, especially for young patients with rapid hair loss, and that hairline design varies among different ethnicities.
October 2002 in “Dermatologic Surgery” The document concludes that careful planning, efficient use of every hair graft, and setting surgical priorities are crucial for successful hair restoration surgery.
10 citations,
April 2020 in “PloS one” Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.
22 citations,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
38 citations,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
13 citations,
February 2018 in “Plastic and Reconstructive Surgery” The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
February 2008 in “Medical & surgical dermatology” Some treatments like topical oxygen and stem cells show promise for wound healing and hair growth, but evidence for modern dressings over traditional ones is limited.
178 citations,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
13 citations,
December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
2 citations,
May 2018 in “Journal of Investigative Dermatology” Mice can regrow hair on wounds due to specific cell interactions and mechanical forces not seen in rats.
132 citations,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
1 citations,
January 2010 in “Elsevier eBooks” The document concludes that local flaps are effective for reconstructive surgery in the head and neck, offering good skin match and function.
47 citations,
August 2005 in “Facial Plastic Surgery Clinics of North America” Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.
22 citations,
August 2010 in “Annals of Plastic Surgery” The study concluded that reconstructive surgery for burn alopecia should be tailored to the scar's size and quality, with different methods recommended for different cases.
November 2018 in “Springer eBooks” The document concludes that hair transplant methods are often selected for provider convenience over patient benefit, highlighting the need for less invasive techniques and careful physician involvement for better results.
January 2007 in “Elsevier eBooks” The document concludes that hair transplantation for Asians should consider unique scalp and hair traits, use small grafts, and combine surgery with medication like finasteride and minoxidil for best results.
15 citations,
November 2008 in “Facial Plastic Surgery” Hair restoration can sometimes result in unnatural-looking hair, wide scars, and poorly designed hairlines, but these issues can be corrected with careful planning, various techniques, and possibly medical therapy.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
2 citations,
March 2023 in “Annals of Translational Medicine” The analysis shows the U.S. leads in tissue expansion research, mainly for breast reconstruction, with a slightly higher complication rate when using acellular dermal matrix.
9 citations,
July 1992 in “Clinics in Dermatology” Scalp reduction surgery can effectively treat male pattern baldness when tailored to the patient and performed with care to minimize complications.