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The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Endoscopic-assisted facelifting is safe and effective with minimal complications and excellent long-term results.

Yak belly hair has higher porosity and is less stiff than human hair, making it absorb dye better but less suitable as a direct substitute for hair dyeing.

Traditional Chinese Medicine and acupuncture may improve Polycystic Ovarian Syndrome symptoms and reduce costs, but more research is needed.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

RF energy is used in medical and beauty treatments to heat tissues, tighten skin, and reduce fat safely.

Low-frequency electromagnetic fields can boost molecules related to hair growth in human skin cells.

Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

Pneumatic Skin Flattening (PSF) significantly reduces pain during laser and IPL hair removal.

The microneedle device with rapamycin and epigallocatechin gallate effectively promoted hair regrowth in mice.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

5% minoxidil foam used once daily is as effective as 2% minoxidil solution used twice daily for hair loss in women, but with fewer side effects like itching and dandruff.

Reflectance confocal microscopy is useful for diagnosing and monitoring skin diseases, but it has limitations and requires expertise for correct use.

Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.

Different treatments for Hidradenitis suppurativa range from antibiotics and hormonal therapies to surgery, depending on severity.

3D bioprinting in plastic surgery could lead to personalized grafts and fewer complications.

Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.

Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.