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Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Finasteride causes harmful organ changes in female mice.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Oestrogens are key for bone growth during puberty in both boys and girls.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Doctors need to be better prepared to assess and treat obesity in patients.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Alefacept showed some effectiveness for alopecia areata but needs more research.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.