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Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Surgery can be a safe and effective option for infertile women with PCOS who don't respond to medication and want to get pregnant.

Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.

Bimatoprost is effective for growing longer, thicker, and darker eyelashes.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.

Finasteride use is not clearly linked to an increased risk of male breast cancer.

Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.

Healthy lifestyle changes can significantly improve skin health as you age.

Natural products and phytochemicals may help with hair regrowth, but more research is needed.

Hemp is a promising ingredient for skin products due to its healing and soothing properties.

Tadalafil and Finasteride may help treat aggressive melanoma.

Cannabidiol shows promise as an effective treatment for acne.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

CBD may improve skin and hair health, but its effective use and safety need more research.

Metformin might help treat certain skin conditions, but more research is needed.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.