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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Testosterone's muscle-building effects do not require its conversion to DHT.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Some common medications can harm male fertility, but many effects can be reversed.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

New compounds may soon be tested to treat excessive hair growth in women.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.