November 2020 in “Journal of The American Academy of Dermatology” The conclusion is that many small genetic variations influence claw disorders in cows, and using genomic selection could help reduce these disorders.
1 citations,
October 2023 in “Frontiers in Oncology” Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
July 2023 in “Developmental medicine and child neurology/Developmental medicine & child neurology” DFMO treatment improves hair growth, muscle tone, and development in Bachmann-Bupp syndrome patients.
153 citations,
June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
61 citations,
April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
29 citations,
November 2022 in “Nature Medicine” Genetic variations greatly affect individual metabolism and can impact health and disease risk.
11 citations,
December 2017 in “Orphanet Journal of Rare Diseases” A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.
6 citations,
June 2012 in “PloS one” A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
September 2022 in “Scientific Reports” Scalp melanoma is more common and easier to diagnose early in people with androgenetic alopecia due to sun damage.
49 citations,
June 2019 in “eLife” Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.
6 citations,
February 2022 in “Journal of immunology research” Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
2 citations,
May 2023 in “Journal of Advanced Research” Two mutations in KRT74 and EDAR genes cause sheep to have finer wool.
1 citations,
October 2023 in “Animals” A small dose of Platycladus orientalis leaf extract improves raccoon dogs' growth and health, but higher doses can be harmful.
1 citations,
July 2023 in “Journal of Animal Science and Biotechnology” The SOSTDC1 gene is crucial for determining sheep wool type.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
September 2023 in “Nature Communications” Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.
September 2023 in “Animals” Genes linked to wool fineness in sheep have been identified.
June 2023 in “Food frontiers” Ginsenoside CK, found in Panax ginseng, can prevent hair loss by controlling certain growth pathways and promoting hair follicle development.
March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
February 2023 in “Journal of Advanced Research” A new method using Platelet-rich Plasma (PRP) in a microneedle can promote hair regrowth more efficiently and is painless, minimally invasive, and affordable.
73 citations,
December 2015 in “Nature Genetics” Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
61 citations,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
32 citations,
December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
21 citations,
November 2019 in “Molecular & Cellular Proteomics” Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.
16 citations,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.