15 citations
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April 2024 in “Animals” This study examined cashmere goats using whole-genome resequencing data and found that the Inner Mongolia cashmere goat had the lowest inbreeding coefficient, with genes identified linked to fiber, fertility, disease resistance, and growth, which can inform future breeding efforts.
7 citations
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June 2024 in “iScience” This review highlights the significant role of androgens in the development and progression of cervical cancer, emphasizing the need for further research to understand their impact on the disease and improve prevention and treatment strategies in regions with limited HPV screening.
February 2024 in “International Journal of Molecular Sciences” This review outlines the functional anatomy, pathology, and molecular mechanisms of androgenetic alopecia, emphasizing the need for multi-omics approaches to better understand this condition's biology.
122 citations
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January 2006 in “Molecular & Cellular Proteomics” This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.
61 citations
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July 2022 in “Journal of Nanobiotechnology” This study found that carbon dots derived from fucoidan effectively inhibit Enterococcus faecalis and its biofilm, offering a promising approach for managing biofilm-associated persistent endodontic infections.
49 citations
,
June 2019 in “eLife” This study reported the discovery of large-scale haplotypes (cenhaps) in human centromere regions, revealing deep genetic diversity, including introgressed Neanderthal and ancient African lineages.
47 citations
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January 2024 in “iScience” The researchers reported that stress-induced keratins in human skin are expressed at lower levels than those in healthy skin and are co-regulated with genes involved in differentiation, inflammation, and immunity, rather than replacing keratins of normal differentiation or indicating cell proliferation.
30 citations
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December 2014 in “BMC Genetics” This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.
26 citations
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September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
19 citations
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June 2020 in “BMC Cancer” This study reported that genetic changes in trichilemmal carcinoma resemble those in other skin cancers, with TP53 mutations associated with aggressive clinical outcomes.
13 citations
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August 2023 in “Developmental Cell” In this study, researchers observed that mechanosensory neurons initially develop similar morphologies across different skin regions but diverge post-natally, adapting to the type of skin they innervate, with bone morphogenetic protein signaling crucial for forming Meissner corpuscles in glabrous skin.
11 citations
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January 2025 in “Regenerative Therapy” This review highlights the potential of bioengineered dermal scaffolds in tissue engineering to enhance wound healing by mimicking the dermal structure and supporting cellular processes, while also discussing recent advancements and challenges in scaffold technology.
11 citations
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December 2024 in “Stem Cell Research & Therapy” In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.
8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
6 citations
,
February 2022 in “Journal of immunology research” This study observed that exosomes from adipose-derived stem cells promoted hair growth by enhancing dermal papilla cell proliferation and activating signaling pathways, suggesting potential for treating immune-mediated alopecia.
5 citations
,
October 2021 in “American Journal of Medical Genetics Part A” This case report identifies a novel maternally inherited MBTPS2 variant associated with an expanded phenotypic spectrum of BRESHECK syndrome, including cytopenias, bone marrow fibrosis, and chronic diarrhea.
4 citations
,
January 2023 in “Marine Drugs” This review explores enzyme inhibitors from gorgonians and soft corals and highlights their potential industrial and biomedical applications, but it reports no new experimental results.
2 citations
,
November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
2 citations
,
May 2023 in “Journal of Advanced Research” In this study, researchers identified two genetic mutations associated with producing finer and denser wool in fine-wool sheep, involving the genes KRT74 and EDAR, which may guide future breeding efforts to enhance wool quality.
1 citations
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November 2025 in “Science Advances” This research identified two genetic variants that influence the white-spotted coat patterns in Holstein-Friesian cattle, involving regulatory changes in the MITF and KIT genes, confirmed through mouse models, along with possible effects on coat patterns in other cattle breeds.
1 citations
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September 2025 in “Wound Repair and Regeneration” This study found that an acellular dermal matrix derived from tilapia skin significantly accelerated wound healing and improved tissue regeneration quality in mouse and pig models compared to a commercial porcine-derived matrix, suggesting its potential as a safe, cost-effective bioscaffold for skin repair.
1 citations
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September 2025 in “JEADV Clinical Practice” This review highlights the need for inclusive dermatology practices to address variations in skin conditions globally by incorporating tools like AI, teledermatology, and culturally competent education.
1 citations
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October 2023 in “Animals” This study found that supplementing raccoon dogs' diets with 0.25 g/kg Platycladus orientalis leaf extract improved growth performance and altered intestinal microbiota, but higher doses may have adverse effects.
1 citations
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July 2023 in “Journal of Animal Science and Biotechnology” This study discovered that lambs with coarse, ancestral-like wool in a population of modern fine wool sheep exhibited overexpression of the SOSTDC1 gene, linked to epigenetic changes, which helps understand the development and diversification of wool types in sheep breeding.
May 2026 in “Theranostics” This study found that the DKK3-CKAP4 signaling axis is involved in fibroimmune remodeling in androgenetic alopecia and that targeting this pathway may restore a regenerative hair follicle environment, offering a potential therapeutic strategy to counteract hair follicle miniaturization.
March 2026 in “Dermatopathology” This study found that sebaceous gland-derived cutaneous adnexal carcinomas exhibited the highest frequency of genomic alterations compared to other tumor types.
December 2025 in “Medical Sciences” This study critically reviewed recent evidence (2020–2025) on treatments like platelet-rich plasma, photobiomodulation, stem cells, and exosomes for androgenetic alopecia, finding emerging but limited efficacy data and emphasizing the need for standardized protocols to enhance transparency and patient safety.
December 2025 in “Journal of Inflammation Research” This study highlights ongoing inequities in access and outcomes for inflammatory skin diseases in Latin America and emphasizes the need for regional registries, harmonized clinical guidelines, and policy reforms to improve equitable dermatologic care.
November 2025 in “Bioactive Materials” In this study, researchers developed a novel nucleic acid nanoparticle system incorporating quercetin, which they found enhances functional hair follicle regeneration and maintains epithelial structure stability in androgenetic alopecia by regulating hair follicle stem and dermal papilla cells.
November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.