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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

New psoriasis treatments are effective but come with side effects and risks.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Vitamin D might help treat some types of hair loss, but more research is needed.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Good nutrition is crucial for healthy hair and can help with hair loss without medication.

New skin treatments in 1987-1988 showed effectiveness for various conditions, but some had side effects or risks.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Good feather growth in poultry needs the right balance of proteins, amino acids, minerals, and vitamins.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

Hair loss is a frequent long-term effect of COVID-19, and oral minoxidil is the most common effective treatment.

The document concludes that managing Dunnigan-Type Familial Partial Lipodystrophy involves treating associated health issues and using medications like metformin and leptin replacement.

VDR regulation varies by tissue and is crucial for its biological functions.

Some diets and supplements might help with skin disorders, but their effectiveness varies and more research is needed.

Eating a balanced diet with vitamins, micronutrients, and antioxidants is important for hair health and can help with hair loss.

Adding hyaluronic acid helps create larger artificial hair follicles in the lab.

The document concludes that parathyroid diseases have a range of clinical features and outcomes, with some conditions being treatable and others having a high risk of mortality.

Combination therapies might work better for some vitiligo patients, but results vary.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.

Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.

Vitamin D levels do not significantly relate to the causes of PCOS or DOR in infertile patients.

People with alopecia areata have much lower Vitamin-D levels than healthy individuals.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Men with early hair loss have lower vitamin D levels.