April 2025 in “Regenerative Therapy” This study found that PRP-Exos may stimulate hair follicle growth and enhance regeneration in cases of AGA by activating the Wnt/β-Catenin signaling pathway, showing potential both in vitro and in vivo.
October 2024 in “Skin Appendage Disorders” This bibliometric analysis reported that PRP is most frequently studied for hair restoration, especially in placebo-controlled trials, although differences in PRP preparation and outcome measures challenge result consistency across studies.
August 2024 in “PLoS ONE” This study reviewed randomized controlled trials to assess whether adding platelet-rich plasma injections to a Minoxidil regimen offers any benefit in treating androgenetic alopecia, but results are not reported in the abstract.
June 2024 in “Clinical and Experimental Obstetrics & Gynecology” In this study, women with recurrent implantation failure after IVF/ICSI had significantly lower platelet, plateletcrit, and lymphocyte counts, but these parameters were not effective for predicting the condition.
January 2024 in “Journal of Education, Health and Sport” This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.
In this study, a 46-year-old patient with alopecia areata experienced successful hair regrowth and improved quality of life after three monthly applications of platelet-rich plasma, which the authors noted is a relatively effective, safe, and minimally invasive treatment option.
May 2022 in “Acta scientific dental sciences” This article discusses the use of platelet concentrates in regenerative surgeries for periodontal and bone defects but presents no new clinical results, emphasizing their potential benefits over traditional methods.
January 2019 in “Springer eBooks” Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
December 2021 in “International Journal of Research in Dermatology” This review examines the use of platelet-rich plasma for treating alopecia and highlights current challenges in preparation standards and efficacy, without presenting new clinical findings.
March 2019 in “European archives of medical research” In this study, PRP injections were found to improve hair density and quality in patients with androgenetic alopecia, with a significant reduction in hair loss and high patient satisfaction after three treatment sessions over several months.
45 citations
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March 2013 in “European Journal of Plastic Surgery” In this retrospective study, PRP injections for alopecia were found to improve hair volume and quality, with high patient satisfaction, particularly in those with less than 2 years of hair loss.
August 2026 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma showed similar efficacy to intralesional triamcinolone acetonide for treating mild patch-type alopecia areata, offering a potential alternative with fewer steroid-related side effects.
1 citations
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January 2014 in “Hair therapy & transplantation” This review discusses various treatment options for Alopecia Areata, focusing on both medical and psychological approaches, and reports no new clinical results.
2 citations
,
July 2002 in “BJUI” Finasteride can cause low platelet count in rare cases.
June 2024 in “Annals of the College of Medicine Mosul/Annals of the College of Medecine” This study explored the use of microneedling for dermatological disorders, highlighting its benefits like increased collagen and elastin production, dermal thickening, and skin rejuvenation, making it suitable for conditions such as scars, stretch marks, and photoaged skin.
January 1992 in “Filosofia oggi” This article discusses the affordability and safety of platelet-rich plasma gel production but presents no new research findings.
29 citations
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August 2017 in “Skin appendage disorders” This study found that IGF-1 likely plays a crucial role in regulating hair growth and alopecia, with balding scalp follicles secreting less IGF-1 than nonbalding counterparts.
March 2013 in “Revista Brasileira de Cirurgia Plástica” This article reviews advances in hair transplant techniques such as megasessions of micro and mini grafts, highlighting platelet growth factors' potential to enhance hair density, without reporting new clinical findings.
31 citations
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December 2023 in “Middle East Fertility Society Journal” This review discusses the relationship between polycystic ovary syndrome and inflammation, highlighting various inflammatory markers, but reports no new clinical results.
This study observed that the extract of Ginseng Radix et Rhizoma promoted hair growth in C57BL/6J mice by enhancing local perfusion and inhibiting platelet aggregation.
290 citations
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August 2021 in “Clinical Reviews in Allergy & Immunology” JAK inhibitors show promise for treating alopecia areata, but more research is needed.
28 citations
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September 2008 in “Current Pharmaceutical Design” This review discusses hypersensitivity reactions to anticoagulants like ASA and heparins, highlighting their rare but potentially life-threatening nature, and emphasizes the need for meticulous allergy testing to find safe alternatives.
2 citations
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June 2022 in “Cosmoderma” This review discusses regenerative medicine's applications in dermatology, highlighting the need for quality clinical trials to optimize treatments like PRP, stem cells, and exosomes, and reports no new results.
July 2023 in “IntechOpen eBooks” This review highlights that alopecia areata, a common type of hair loss, currently lacks preventive or curative treatments, and traditional therapies such as minoxidil and corticosteroids offer inconsistent results, necessitating patient-consensual treatment planning.
January 2019 in “Springer eBooks” PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
3 citations
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September 2017 in “Stem cell investigation” This review discusses the various roles of skin-resident dermal white adipose tissue in hair growth inhibition, antibacterial responses, and wound healing, reporting no new empirical findings.
2 citations
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March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
1 citations
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September 2020 in “Medicina y Laboratorio” This review examines platelet-rich plasma therapy for musculoskeletal and soft tissue injuries and reports no firm evidence supporting its routine use due to poor study design and inconsistent results.
December 2025 in “Cosmetics” This review synthesizes recent molecular and preclinical advances in alopecia areata and androgenetic alopecia, highlighting how interventions targeting specific intracellular signaling pathways and utilizing stem cell technologies can support precision regrowth and structural follicle reconstruction.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.