51 citations,
March 2014 in “Nature Communications” Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
31 citations,
October 2010 in “Journal of the European Academy of Dermatology and Venereology” Some people with heavy hair shedding might actually have a hidden form of alopecia, which can be identified by specific hair changes.
14 citations,
July 2011 in “Experimental Dermatology” Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
8 citations,
May 2018 in “The Journal of Allergy and Clinical Immunology” Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
208 citations,
December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
67 citations,
December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
56 citations,
May 2017 in “Nature Cell Biology” Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
52 citations,
June 2013 in “The Journal of Clinical Endocrinology and Metabolism” The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
39 citations,
October 2014 in “Schweizerische medizinische Wochenschrift” Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
12 citations,
August 2020 in “Frontiers in Genetics” H19 boosts hair growth potential by activating Wnt signaling, possibly helping treat hair loss.
7 citations,
January 2023 in “Frontiers in cell and developmental biology” Celsr1 is crucial for skin cell alignment, while Celsr2 has little effect on this process.
2 citations,
April 2021 in “International Journal of Molecular Sciences” The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
1 citations,
October 2023 in “European journal of histochemistry” Ozone and procaine boost the release of healing factors in platelet-rich plasma.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
166 citations,
September 2011 in “Dermatologic Surgery” Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.
125 citations,
May 2019 in “Phytomedicine” Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
77 citations,
April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
70 citations,
August 2020 in “Nanomaterials” Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.
67 citations,
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.
65 citations,
January 2013 in “Cochrane library” Some systemic treatments work for nail psoriasis but can have serious side effects.
40 citations,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
39 citations,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
39 citations,
January 2008 in “Journal of Endocrinology” SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
32 citations,
January 2000 in “Skin pharmacology and physiology” Certain substances that block a specific protein help promote hair growth.
26 citations,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
25 citations,
July 2019 in “Journal of drug delivery science and technology” Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
19 citations,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
14 citations,
November 2013 in “Journal of the American Society for Horticultural Science” Glycine slows main root growth but boosts root hair growth in habanero peppers.
11 citations,
October 2020 in “Plant biotechnology journal” Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
10 citations,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” FP-1 is a key protein in rat hair growth, active only during the growth phase.