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Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

The document explains how male reproductive hormones work and affect the body.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Lower SHBG levels may increase the risk of PCOS.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

New therapies are being developed that target integrin pathways to treat various diseases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Vitamin D is important for skin health and can affect various skin diseases.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.

Eclipta prostrata is a medicinal plant that helps treat diseases, protects the liver and nerves, and promotes hair growth.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

Azathioprine may help treat severe alopecia areata, but more research is needed.