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Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Chemokine signaling is important for hair development.

Fat cells are important for tissue repair and stem cell support in various body parts.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

GLI2 increases follistatin production in human skin cells.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Understanding skin structure and development helps diagnose and treat skin disorders.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

Targeting colon cancer stem cells might lead to better treatment results.