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New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

Women with PCOS have higher risks of heart disease, type 2 diabetes, and endometrial cancer.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

Long-term finasteride use doesn't change bone density or metabolism.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Mice with CBS deficiency are healthier on a low-methionine diet.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Finasteride effectively treats male hair loss, increasing length and thickness.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Oestrogens are key for bone growth during puberty in both boys and girls.