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Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

Adipose-derived stem cells may help with hair loss, but more research is needed.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.

Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.

Hair growth and development are controlled by specific signaling pathways.

Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.