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Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Switching to extended-release divalproex sodium improved patient-reported tremor but did not change seizure frequency or most side effects.

New genetic locations explain much of hair color variation in Europeans.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Hyperandrogenism, often causing excessive hair growth and acne, can be treated with methods like weight reduction, hair removal, various medications, and in the case of acne, topical treatments.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Monitoring new epilepsy drugs after they're sold is crucial to find rare and long-term side effects that initial tests might miss.

Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

PRP can help treat hair loss but needs standardized methods for best results.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.

Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.

Hair follicles in mutant mice self-organize into ordered patterns within a week.

Combining fractional CO2 laser and PRP is very effective for treating female hair loss.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Malassezia infection may cause refractory acne, and antifungal treatments can help.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The document suggests a young mother use effective contraception like the Copper-T IUD while considering her health and the need for STD prevention.