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Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

MicroRNA-21 could help diagnose and treat skin fibrosis.

The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

FKBP10 and FBN2 are key proteins for hair growth in cashmere goats.

Not getting enough minerals can lead to health problems and shorter lifespans.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Researchers found a way to grow cashmere goat hair cells in a lab and discovered that certain conditions improve these cells' growth and characteristics.

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Both human and animal-derived small extracellular vesicles speed up skin healing equally well.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Long-COVID has diverse, long-term health impacts, especially in young people.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.