In this study, testosterone treatment was found to increase blood pressure in rats, potentially through mechanisms involving sodium and water retention in the kidneys and changes in specific gene expressions in the brain.
2 citations
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June 2023 in “Research in Pharmaceutical Sciences” Bhamrung-Lohit may help with inflammation and oxidation.
January 2026 in “Journal of Ayurveda and Integrated Medical Sciences” In this case report, a multimodal Ayurvedic treatment combining Gunjadi Taila, Rasayana therapy, and Prachhanna Karma successfully reduced hair fall, scalp itching, dandruff, and dryness in a 32-year-old male, suggesting its effectiveness for managing these scalp disorders.
129 citations
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February 2006 in “Andrology” This article reviews considerations and guidelines for testosterone therapy in older men with low testosterone levels but does not provide new clinical results, emphasizing the need for ongoing evaluation and careful management, particularly regarding risks related to prostate and cardiovascular health.
77 citations
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May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
17 citations
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February 2019 in “Journal of Clinical Medicine” This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.
February 2026 in “Cureus” This case report highlights the complexity of diagnosing and treating late-onset hypogonadism in a patient with major depressive disorder, suggesting parallel evaluation of symptoms, medication effects, and shared diagnostic planning.
This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.
January 2018 in “Journal of translational science” In this study, oral broccoli sprouts intake did not affect plasma androgen levels in males, while alfalfa sprouts intake increased testosterone and DHT levels, which may help prevent male late onset hypogonadism.
This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.
November 2024 in “International Journal Of Ayurvedic And Herbal Medicine” In this case report, a 25-year-old male with patchy hair loss showed marked symptomatic improvement following an Ayurvedic treatment regimen at SDM Ayurveda Hospital, supporting Ayurveda's potential effectiveness in managing Indralupta, akin to Alopecia areata.
October 2019 in “International Journal of AYUSH Case Reports” This case study reported that a 29-year-old male patient with alopecia areata patchy experienced hair regrowth and relief from scalp itching and dandruff after using medicinal leech therapy and specific internal medicines for three months.
20 citations
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March 2022 in “Journal of clinical medicine” This study found that late-onset hypogonadism is relatively common in male patients with long COVID, even among those under 50, and serum free testosterone measurement can help reveal this condition.
280 citations
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May 2005 in “Andrology” This document outlines recommendations from an international panel on testosterone therapy for aging men with late-onset hypogonadism, emphasizing the need for careful assessment and monitoring due to limited long-term safety data.
1 citations
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May 2008 in “Journal of Experimental Biology” This collection of reviews, edited by Ken Lukowiak and Janis Weeks, explores diverse sensory systems across species, including olfaction, echolocation, magnetoreception, and visual adaptations, without presenting new experimental results.
January 2026 in “International Ayurvedic Medical Journal” This case report observed significant improvement in a 23-year-old male with Khalitya/Androgenetic alopecia after undergoing Ayurvedic management.
3 citations
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September 2021 in “Annals of Plastic Surgery” In this preliminary study, topical treatment with oxygen-carrying micro/nanobubbles hastened the healing of full-thickness burn wounds in a rodent model, compared to saline-treated controls.
1 citations
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January 2019 in “Indian Journal of Public Health Research and Development” This study found that androgenic alopecia significantly impairs quality of life among adults, with higher impairment observed in males and those who are employed.
October 2025 in “Progress In Microbes & Molecular Biology” This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
113 citations
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June 2010 in “Biological Chemistry” This study found that mice deficient in the enzyme cathepsin L exhibited impaired degradation of autophagolysosomal content, leading to an accumulation of large, abnormal vesicles in various tissues.
90 citations
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September 2020 in “Journal of Investigative Dermatology” This study found that increasing the levels of specific microRNAs from the miR-17∼92 cluster improved wound healing in mice by reducing inflammation, suggesting a potential therapeutic approach for chronic wounds.
71 citations
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May 2024 in “New England Journal of Medicine” This study investigated the impact of the JAK inhibitor ruxolitinib on APS-1 patients, reporting that treatment decreased excessive T-cell-derived interferon-γ, normalized inflammatory markers, and led to remission of several autoimmune symptoms without serious adverse effects.
51 citations
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January 2004 in “European Journal of Cell Biology” Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.
43 citations
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February 2013 in “Developmental dynamics” This study found that Eda and activin A regulate Foxi3 expression, which may contribute to the development of hypohidrotic ectodermal dysplasia by affecting Foxi3 activity in ectodermal appendages like hair and teeth.
29 citations
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October 2016 in “Cell death and differentiation” This study found that in squamous cell carcinomas, the inhibition of the tumor-suppressor function of TAp73β by ΔNp63α occurs through promoter squelching, not direct protein interaction.
22 citations
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July 2006 in “Annals of The Royal College of Surgeons of England” This case report aims to raise physician awareness about 'toe-tourniquet' syndrome, which can lead to digit loss if not promptly treated, and to prevent its misdiagnosis as child abuse.
21 citations
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July 2017 in “Journal of Cosmetic and Laser Therapy” This review discusses the research and development of vesicular carriers to enhance the delivery and effectiveness of active ingredients in cosmetic products, reporting no new clinical results.
18 citations
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January 2016 in “Elsevier eBooks” This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.
15 citations
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February 2014 in “BMC Research Notes” This study found that male androgenic alopecia patients using the X5 hair laser device showed a statistically significant increase in hair growth over a 26-week period.
11 citations
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June 2020 in “FEBS Journal” This review discusses the regulation of myeloid cell networks in barrier tissues and how various factors influence immune homeostasis, but it reports no new experimental results.