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A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Finasteride can reduce fertility in some men, but stopping it increases sperm count.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The study suggests smoking is common in HS patients but its role is unclear, and more research is needed to understand HS causes.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Researchers developed a new method to identify animal hair in textiles, which is effective for various fibers and more reliable than previous methods.

Hair loss treatments work better with lifestyle changes.

High levels of androgens during early development may cause PCOS-like symptoms.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.