January 2025 in “Dermatologic Therapy” This study found that ablative fractional carbon dioxide laser treatment improved skin fibrosis, reduced skin hardening, and enhanced hair follicle growth in localized scleroderma patients, with significant improvements across several clinical measures and no severe adverse effects observed.
June 2026 in “Journal of Korean Medicine” This case report describes a 51-year-old male who developed localized hair growth exclusively at sites of repeated cupping therapy on the neck and shoulder, suggesting a possible link between long-term cupping and localized acquired hypertrichosis.
5 citations
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December 2018 in “Annals of plastic surgery” In this report, seven burn patients developed hypertrichosis after undergoing pressure garment/silicone therapy intended to prevent hypertrophic scarring.
84 citations
,
January 1990 in “Journal of The American Academy of Dermatology” This study reported successful repigmentation without scarring in patients with localized and segmental vitiligo after epidermal grafting, but the Koebner phenomenon hindered similar results in some with generalized vitiligo.
16 citations
,
July 2002 in “Australasian Journal of Dermatology” This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.
9 citations
,
November 2015 in “JAMA dermatology” This case study describes an elderly woman with distinctive black hair patches and scalp pigmentation, but it does not provide a diagnosis or new findings.
39 citations
,
March 1976 in “British Journal of Dermatology” This article reviews the use of intralesional steroid therapy in dermatology, highlighting its application in conditions like nail disorders and cystic acne, but it reports no new clinical results.
4 citations
,
January 2014 in “Indian journal of paediatric dermatology” This review discusses the use of methotrexate for pediatric dermatoses and reports increased use in certain conditions like psoriasis, but mainly isolated case reports for others.
April 2022 in “Authorea (Authorea)” This study reports two cases where localized prostate cancer with low PSA levels was incidentally detected through CT scans performed for other medical reasons.
231 citations
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October 1999 in “Journal of Clinical Investigation” This study found that administering an adenovirus vector to increase Sonic hedgehog gene expression in mouse skin accelerated the transition of hair follicles into the growth phase, promoting hair growth.
August 2026 in “PLoS ONE” This study will evaluate the clinical efficacy, patient-reported outcomes, and economic impact of the PAXMAN® PSCS 2 automated scalp cooling system versus standard cold-cap therapy to prevent chemotherapy-induced hair loss in women with localized breast cancer during anthracycline and taxane treatment.
March 2022 in “International journal of biology, pharmacy and allied sciences” This case study describes the successful management of alopecia areata in an 18-year-old female patient using Shaman Aushadhi.
49 citations
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May 2020 in “The Scientific World JOURNAL” This position paper from the Italian Mesotherapy Society discusses the application of intradermal therapy based on scientific evidence, highlighting its potential benefits for certain localized conditions, although it acknowledges the lack of randomized clinical trials for some uses.
2 citations
,
January 2017 in “International Journal of Trichology” This case report describes the trichoscopic and histological features observed in a 7-year-old boy with morphea en coup de sabre and details the positive response to systemic immunosuppressive therapy.
April 2022 in “Australasian Journal of Dermatology” This case report describes a rare presentation of recurrent plaque psoriasis on the penile shaft, which was controlled with systemic therapy after topical treatments failed.
June 2025 in “Journal of Drug Delivery Science and Technology” A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.
This review outlines the applications of intralesional steroid therapy, particularly triamcinolone acetonide, in several dermatological conditions and suggests further trials for certain uses but reports no new clinical findings.
9 citations
,
January 2015 in “Annals of dermatology/Annals of Dermatology” This retrospective study concluded that alopecia areata in elderly patients showed mild severity and a favorable treatment response, with no link found between hair graying and the extent of hair loss.
July 2025 in “Pharmaceutics” This study found that Annexin A5 significantly reduced fibrosis and inflammation in both preventive and therapeutic contexts in a bleomycin-induced localized scleroderma mouse model, demonstrating its potential anti-fibrotic and anti-inflammatory effects for treating fibrotic diseases.
35 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This study found that intralesional triamcinolone acetonide is effective for treating localized patchy alopecia areata, with dermoscopy aiding in early detection of clinical response and adverse effects.
3 citations
,
January 2016 in “Case reports in dermatological medicine” This report discusses a case of localized hypertrichosis that developed after an elderly male with Alzheimer's disease started oral rivastigmine therapy, suggesting a potential link between the drug and hair growth.
April 2026 in “Indian Journal of Dermatology” This study concluded that platelet-rich plasma therapy was as effective as intralesional triamcinolone acetonide in treating localized alopecia areata on the scalp.
June 2022 in “World Journal Of Advanced Research and Reviews” This case report describes successful hair regrowth and repigmentation in a patient with scalp-localized alopecia areata following treatment with Sunetics Laser therapy.
In this case study, a 46-year-old woman with localized discoid lupus erythematosus on her scalp showed significant improvement with a combination of oral hydroxychloroquine and topical pimecrolimus, despite limited success with previous treatments.
7 citations
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August 2025 in “Journal of Nanobiotechnology” This review highlights the potential of microneedles and nanomedicine in advancing tissue regeneration, emphasizing their innovative, localized, and minimally invasive approaches as promising solutions to current challenges in treating chronic wounds and degenerative diseases.
August 2023 in “Dermatologic Surgery” This study reviewed evidence suggesting that certain types of wounds might stimulate localized hair growth in humans, noting anecdotal reports and mixed efficacy of treatments like microneedling and lasers for androgenetic alopecia, but emphasized that further research is needed.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that MPZL3 plays a crucial role in regulating the hair cycle clock in mice, with its absence leading to accelerated hair follicle cycling and suggesting potential therapeutic pathways for alopecia treatment.
19 citations
,
April 2014 in “Veterinary Dermatology” In this case report, two cats with asthma developed localized skin lesions associated with inhalant glucocorticoid use, which resolved after adjusting treatment and administering milbemycin.
3 citations
,
August 2020 in “Journal of The American Academy of Dermatology” This study observed that patients with scalp dysesthesia frequently exhibited cervical spine degenerative changes, which localized predominantly in the lower cervical spine, and reported modest symptom improvement with neuropathic pain medications and physical therapy.
2 citations
,
November 2023 in “Curēus” This review explores platelet-rich plasma's role in wound healing and discusses its potential as a broadly applicable therapeutic option, but it reports no new clinical results.