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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Fat-related cells are important for initiating hair growth.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Testosterone therapy increases bone density in older men with low testosterone levels.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Zinc is effective for treating various skin conditions, including warts and acne.

Blood vessels and specific genes help turn cartilage into bone when bones heal.