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A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Sex hormones affect brain cells differently in males and females.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Hair loss can be managed with treatments like minoxidil, finasteride, and others, but there are still gaps in effectiveness and off-label usage is increasing.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Anti-Müllerian hormone is a specific marker for ovarian issues in women with conditions like PCOS.

Thyroid hormone may be useful for treating various skin conditions and needs more research.

SHBG may be a useful early indicator and treatment target for PCOS.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.