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In this study, 0.5%-1.0% anthralin cream led to a cosmetic response in 25% of patients with severe alopecia areata, despite common side effects like pruritus and erythema.

This study reported 14 cases of frontal edema following mesotherapy for androgenetic alopecia, suggesting clinicians should be aware of this potential side effect.

In this study, microneedling and intralesional corticosteroid injections in patients with alopecia areata showed similar hair regrowth effectiveness, with microneedling resulting in more uniform but less dense regrowth and fewer side effects.

This study observed that combining nonablative fractional laser treatment with topical minoxidil led to hair regrowth in Chinese alopecia areata patients, noting complete regrowth in some patients and no relapse in the majority at a one-year follow-up, without reported side effects.

This study found that intralesional triamcinolone acetonide at both 5 mg/mL and 10 mg/mL concentrations had similar effectiveness and safety for treating patchy alopecia areata on the scalp, with no significant difference in response rates or side effects between the two dosage groups.

This randomized controlled trial found that intralesional injections of triamcinolone were significantly more effective than platelet rich plasma for treating alopecia areata on the scalp, although platelet rich plasma was considered a viable alternative due to its lack of serious side effects.

This article discusses the potency grading of steroid skin creams and highlights that very potent or potent steroids (grades I and II) can cause significant side effects, especially in children.

This review discusses the role of the mineralocorticoid receptor in skin biology, highlighting its potential involvement in keratinocyte and hair physiology, and proposes it may affect the side effects of glucocorticoid use.

This study reports cutaneous atrophy and alopecia in four patients following greater occipital nerve blockade with triamcinolone and lidocaine, suggesting that alternative steroids may reduce these side effects.

This study reported that after 7.5 months of treatment, topical Alfatradiol significantly increased anagen hair rates in women and men with androgenetic alopecia, with minimal side effects.

This case report describes a woman who experienced frontal edema after topical minoxidil application following mesotherapy, noting that excessive absorption of minoxidil may cause localized vasodilatory side effects.

This study found that intralesional Vitamin D3 injections were comparable in efficacy to intralesional triamcinolone for patchy alopecia areata, with a non-significant trend towards better outcomes and fewer local adverse effects.

This study suggests that nanotechnology-based drug delivery systems can improve the targeted, sustained delivery and stability of dermatological treatments, potentially leading to better outcomes and reduced side effects for various aesthetic skin conditions, though further clinical trials are needed to confirm these benefits.

This source reviews clinical research progress on injection therapies for androgenetic alopecia, highlighting that methods like platelet derivatives, botulinum toxin, and stem cells may offer precise hair follicle targeting and reduced side effects compared to traditional treatments.

In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.

This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.

This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.

This review reports no new results and discusses various topical treatments, noting that fluocortin butyl ester offers anti-inflammatory effects without systemic side effects, while combinations outperform single-agent therapies in managing hyperpigmentation.

Dutasteride 0.5mg was found to be more effective than finasteride 1mg in treating male pattern hair loss, with similar side effects.

This systematic review explored the potential of cetirizine, an anti-inflammatory antihistamine, as a complementary treatment for androgenetic alopecia, reporting that it might help prevent hair follicle miniaturization by reducing inflammation and modulating immune activity, without notable side effects.

This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.

This study found that transdermal delivery of finasteride using biomimetic Platycladi cacumen-derived nanovesicles enhanced hair regrowth in a mouse model of androgenetic alopecia, outperforming minoxidil by improving skin permeation, reducing oxidative stress, and boosting local drug retention.

This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.

This case study reports significant hair regrowth in a patient with alopecia areata using Ayurvedic treatments, which included Nasya with Bindu Taila, Pracchan Karma, and topical therapies with castor leaves and buffalo butter, without causing adverse effects.

This study reports that 11β-HSD1 activity in human skin increases with age and photoexposure, potentially contributing to skin aging and the effects of glucocorticoids.

This study evaluated amphiphilic self-assembling peptides as drug delivery systems and found they effectively ensured prolonged release and therapeutic efficacy for timolol in glaucoma and for chemotherapy agents in cancer treatment, with significant tumor size reduction observed in animal models.

This study found that 1% topical minoxidil significantly promoted hair regrowth in patients with alopecia areata, though it was less effective or ineffective in more severe forms like alopecia totalis and universalis.

The combination of finasteride and minoxidil is as safe and effective as minoxidil alone for improving hair growth in men.

This review summarizes the structural and chemical characteristics of current and novel antiandrogenic drugs but reports no new clinical findings.

This study investigated using baricitinib-loaded mesenchymal stem cell exosomes injected locally in an alopecia areata mouse model and found that this method improved hair regrowth better than baricitinib or exosomes alone, potentially offering a new therapeutic approach for treating alopecia areata.