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The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Fat cells in the skin help start healing and form important repair cells after injury.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Liposomes could improve how skin care products work but are costly and not very stable.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Skin fat helps with body temperature control and has other active roles in health.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Long-term parenteral nutrition without zinc can cause severe zinc deficiency.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.