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The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

The circadian clock influences the behavior and regeneration of stem cells in the body.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

Minoxidil works in liver and outer hair root sheath for hair growth.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Prolactin may affect hair growth differently based on gender and scalp area.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

There is no significant link between male pattern baldness and insulin resistance.

Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.