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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Skin problems are common in people with diabetes and controlling blood sugar can reduce these issues.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Three siblings with a genetic form of rickets showed different symptoms of the disease.

Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Spironolactone most effective for hirsutism, but has side effects.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.