49 citations,
January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
45 citations,
January 2008 in “Drugs” Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
42 citations,
February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
39 citations,
September 2016 in “Expert Opinion on Drug Delivery” New drug delivery methods can make natural compounds more effective and stable.
38 citations,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
28 citations,
September 2014 in “Journal of Clinical Oncology” Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.
12 citations,
February 2003 in “European Urology Supplements” Dutasteride reduces DHT more effectively than finasteride.
11 citations,
January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
10 citations,
June 2014 in “Journal of Pharmacy and Pharmacology” Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.
9 citations,
October 2013 in “PLOS ONE” Dutasteride works better than finasteride for preventing and treating prostate cancer.
8 citations,
December 2021 in “International Journal of Family Studies, Food Science and Nutrition Health” Extra virgin olive oil may boost the immune system and help fight infections like COVID-19.
5 citations,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Rapamycin may help treat Leigh syndrome by targeting protein kinase C.
3 citations,
January 2019 in “Therapeutic advances in urology” WS PRO 160 I 120 mg effectively treats urinary symptoms from BPH with good safety and tolerability.
January 2024 in “Biological & clinical sciences research journal” Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
January 2024 in “Wiadomości Lekarskie” Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.
November 2022 in “CARDIOMETRY” A group has developed therapies that show promise for treating cancer and various other conditions.
Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.
March 2011 in “European Urology Supplements” Gene variation affects prostate issues and hair loss.
41 citations,
February 2021 in “Translational research” Non-coding RNAs could help detect and treat radiation damage.
1 citations,
January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
149 citations,
January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
54 citations,
September 2002 in “Annals of Pharmacotherapy” Herbal treatments can help with early-stage BPH symptoms, but more research is needed.
4 citations,
August 2023 in “Materials” New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
1 citations,
February 2017 in “MOJ bioequivalence & bioavailability” Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
September 2020 in “Current Enzyme Inhibition” Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.
9 citations,
September 2014 in “Cancer Epidemiology, Biomarkers & Prevention” Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.
34 citations,
July 1993 in “PubMed” November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
11 citations,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.