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    Glossary LNCaP cells

    human prostate cancer cells used in research

    LNCaP cells are a type of human prostate cancer cell line commonly used in scientific research. They are derived from a metastatic lesion of human prostatic adenocarcinoma and are used to study prostate cancer biology, including hormone responses and cancer progression.

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    Research 30 of 263

    1. Inhibition of Proliferation of LNCaP Prostate Cells by Corni Fructus Extract Is Associated with a Decrease in the Expression of Benign Prostatic Hyperplasia-Causing Factors Journal of Korean Medicine for Obesity Research · 2021 · 1 citations
    2. Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth Evidence-based complementary and alternative medicine · 2016 · 6 citations
    3. Impact of a Novel Dehydroepiandrosterone Derivative on the Metabolism of RWPE-1 and LNCaP Cell Lines Oriental Journal Of Chemistry · 2026
    4. Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line European Journal of Medicinal Chemistry · 2016 · 11 citations
    5. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    6. Inhibitors of 5α -Reductase Type I in LNCaP Cells from the Roots of Angelica koreana Planta Medica · 2002 · 22 citations
    7. Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells 2023
    8. Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines European Journal of Pharmacology · 2022 · 1 citations
    9. Effects of androgen and valproic acid treatment on androgen- dependent cell line (LnCaP-SF) European Journal of Cancer Supplements · 2008
    10. Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior Journal of Ethnopharmacology · 2014 · 19 citations
    11. Design, Synthesis, and Preclinical Evaluation of Prostate-Specific Membrane Antigen Targeted <sup>99m</sup>Tc-Radioimaging Agents Molecular Pharmaceutics · 2009 · 148 citations
    12. Anti-androgenic effect of sesquiterpenes isolated from the rhizomes of Curcuma aeruginosa Roxb. Fitoterapia · 2012 · 44 citations
    13. The antiandrogenic effect of finasteride against a mutant androgen receptor Cancer Biology & Therapy · 2011 · 20 citations
    14. Synthesis, biological evaluation and molecular docking of 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs containing the piperazine moiety Bioorganic & medicinal chemistry · 2019 · 7 citations
    15. Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase Biological & Pharmaceutical Bulletin · 2018 · 7 citations
    16. Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia Journal of Medicinal Chemistry · 2026
    17. Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study. Journal of molecular structure · 2024
    18. 토마토 추출액 복합체가 전립선 암 세포와 전립선 비대증에 미치는 영향 생약학회지 · 2007
    19. 1116 Novel androgen receptor degrader for androgenetic alopecia (AGA) application Journal of Investigative Dermatology · 2023
    20. 복분자 미숙과 추출물이 전립선암 세포주와 전립선비대 백서모델에 미치는 영향 Journal of the Korean Society of Food Science and Nutrition · 2014 · 1 citations
    21. Anti-Androgen Effects of Extracts and Compounds from<i>Ganoderma lucidum</i> Chemistry & Biodiversity · 2009 · 20 citations
    22. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    23. Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells American journal of physiology. Cell physiology · 2006 · 56 citations
    24. 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives International Journal of Biological Macromolecules · 2011 · 26 citations
    25. Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice International Journal of Molecular Sciences · 2023
    26. Effects of the androgen receptor overexpression in prostate cancer 2007
    27. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    28. RE: EFFECT OF THE DUAL 5α-REDUCTASE INHIBITOR DUTASTERIDE ON MARKERS OF TUMOR REGRESSION IN PROSTATE CANCER 2005
    29. Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists Bioorganic & medicinal chemistry letters · 2017 · 3 citations
    30. The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function American Journal of Pathology · 2003 · 72 citations