14 citations
,
July 2021 in “Bioinformatics” This study demonstrates the use of rPanglaoDB, an R package for combining public single-cell datasets, to create the first unbiased transcriptome profile of fibrocytes, revealing their role in tissue healing.
14 citations
,
June 2021 in “British Journal of Dermatology” This article discusses the BIOMAP consortium's efforts in standardizing data for atopic dermatitis and psoriasis research to facilitate personalized medicine, but it presents no new research findings.
14 citations
,
August 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study found that finasteride maintained chemical and physical stability in various excipient mixtures, which may guide the development of stable topical delivery systems.
14 citations
,
January 2006 in “Journal of Investigative Dermatology” This study found that controlling transferrin receptor expression effectively regulates iron content in the epidermis and hair of transgenic mice.
13 citations
,
April 2020 in “Women s Health Reports” This review discusses the potential benefits of resistance exercise and art therapy for improving body image in breast cancer survivors, highlighting a need for more theory-informed research.
12 citations
,
March 2023 in “Processes” In this study, extracts from Chenopodium quinoa, Glycine max, and Malpighia emarginata demonstrated stability, low toxicity, and effective cleaning potential as surfactants in shampoo formulations, showing performance similar to or better than commercial shampoos in terms of surface and interfacial tension and sebum removal.
12 citations
,
February 2003 in “European Urology Supplements” Dutasteride reduces DHT more effectively than finasteride.
11 citations
,
September 2016 in “Journal of virological methods” In this study, rabies virus antigens were detected in the outer root sheath of the follicle-sinus complex in the muzzle skin of rabid dogs, suggesting its usefulness as an alternative diagnostic specimen.
11 citations
,
January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that LY320236 is a competitive inhibitor of type I and a non-competitive inhibitor of type II steroid 5alpha-reductase, indicating its potential as a dual inhibitor with differing modes of activity.
10 citations
,
April 2018 in “Journal of Mind and Medical Sciences” This article argues that the mind-body problem is a false issue, proposing that the mind merely temporally associates immaterial data with material support without actual interaction.
9 citations
,
June 2024 in “Cell Reports” This study found that hair follicles play a significant role in regulating skin barrier function, with disruptions in the upper hair follicle affecting the epidermis, influencing processes like desquamation and sebum release, and leading to cell movement into the epidermis.
9 citations
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June 2023 in “Cells” This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.
8 citations
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February 2025 in “Pharmaceuticals” This source reviews the potential of polyphenols as therapeutic and preventive treatments for common skin disorders such as acne, fungal infections, dermatitis, alopecia, and skin cancer, emphasizing their anti-inflammatory and antimicrobial effects and ability to penetrate the skin barrier.
6 citations
,
August 2023 in “Journal of Investigative Dermatology” This study investigated how keratinocytes in the skin respond to different iron levels and found they play a significant role in regulating iron homeostasis by storing iron, affecting epidermal differentiation, and influencing inflammation-related gene expression in mice.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.
6 citations
,
June 2017 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study reported that using hair follicles from the scalp in punch-type grafts improved healing in chronic venous ulcers compared to traditional hairless punch grafts.
5 citations
,
June 2024 in “Developmental Cell” In this study, activating TRPV1 nociceptors in mice skin stimulated dormant hair follicles and promoted hair growth through a mechanism involving dermal macrophages, fibroblasts, and neuropeptides, highlighting a new role for nociceptors in tissue recovery after injury.
5 citations
,
April 2024 in “Heliyon” In this study, the researchers found that the chemical composition and color of the brown seaweed *Saccharina latissima* varied significantly depending on the harvesting period, site, and cultivation method, suggesting that environmental conditions play a key role in these variations.
5 citations
,
February 2022 in “Stem cell reports” This study found that thymic stromal lymphopoietin (TSLP) promotes hair growth after skin injury by enhancing the proliferation of specific stem cells in hair follicles.
5 citations
,
August 2021 in “Journal of biological chemistry/The Journal of biological chemistry” This study observed sexually dimorphic effects of reduced Rdh10 on energy metabolism and muscle function in mice, with males experiencing decreased endurance and females showing increased endurance on a high-fat diet.
5 citations
,
October 2020 in “Experimental dermatology” This study reports that during late embryogenesis and early postnatal development, K79-expressing keratinocytes change and die independently of sebaceous glands to form the hair follicle opening, potentially influencing conditions like ingrown hairs or acne.
5 citations
,
October 2010 in “General and Comparative Endocrinology” In this study, pregnant spotted hyenas treated with flutamide and finasteride had lower concentrations of several sex hormones, including testosterone and luteinizing hormone, compared to untreated controls.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.
4 citations
,
June 2021 in “Powder Technology” This study developed finasteride-containing granules using a method that improved follicular targeting for androgenic alopecia and reported potential for easy industrial production.
4 citations
,
October 2017 in “Journal of Mind and Medical Sciences” This overview discusses the mind-body problem and suggests that the brain may be intrinsically part of the mind, processing abstract data without direct interaction, but reports no new research results.
4 citations
,
March 2000 in “Journal of Investigative Dermatology” The gene for Marie Unna hereditary hypotrichosis is located on chromosome 8p21, near the hairless gene.
3 citations
,
September 2021 in “Journal of Clinical Medicine” In this study, fingertip regeneration in mice was associated with specific signaling pathways involving hair follicles and hedgehog signaling, with potential implications for improving human hand injury treatments.
3 citations
,
September 2021 in “International Journal of Molecular Sciences” This study suggests that women with polycystic ovary syndrome may have an increased risk of COVID-19-related cardiac and renal complications, and that weight loss through lifestyle changes could help reduce these risks.
3 citations
,
December 2020 in “Endocrine and metabolic science” This study found that care for transgender Veterans at VANCHCS could benefit from a more consistent, team-based approach to therapy.
2 citations
,
November 2022 in “Bioscience Reports” This review explores the similarities between polycystic ovary syndrome and hemochromatosis in terms of iron overload and suggests that addressing gut dysbiosis might help manage iron levels in these conditions.