13 citations
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September 2024 in “Frontiers in Pharmacology” This review highlighted the pharmacological potential of Mor, noting its protective effects on the kidneys, liver, bones, nervous system, heart, digestive system, skin, and lungs, as well as its anti-obesity and anti-inflammatory properties, revealing areas for future research.
13 citations
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December 2021 in “Toxics” In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.
13 citations
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December 2017 in “Archives of Medical Sciences” This article highlights that rivaroxaban, commonly associated with bleeding risks, may also cause rare non-bleeding adverse effects like liver injury and hypersensitivity.
13 citations
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March 1999 in “Biochemical Journal” In this study, transgenic mice overexpressing the SSAT gene were highly sensitive to polyamine analogues, leading to severe liver changes and high mortality rates after treatment.
13 citations
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March 1962 in “Nature” This study found that zinc content decreases not only in the blood but also in other tissues like the heart, spleen, liver, and kidney of carcinoma patients.
11 citations
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December 2022 in “Arterial Hypertension” This joint position paper by several Polish medical societies examines guidelines and recommendations for managing conditions like obesity, hypertension, and liver disease, underscoring the importance of a collaborative, interdisciplinary approach in treatment. Results are not explicitly reported.
8 citations
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March 2018 in “Journal of Drug Delivery Science and Technology” This study found that treating paracoccidioidomycosis-infected mice with a nanoparticle formulation of itraconazole led to higher drug accumulation in lung, liver, and spleen tissues, improved treatment efficacy, and reduced side effects compared to traditional oral solutions.
8 citations
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October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation” This study found that normal ALT levels in women of reproductive age are linked with metabolic and androgenic abnormalities, suggesting ALT could be used beyond liver disease diagnoses.
7 citations
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January 2021 in “Food & Function” In this animal study, Castanea sativa Mill. flower extract did not significantly affect prostate tumorigenesis but demonstrated antioxidant and anti-inflammatory effects on the prostate and liver.
6 citations
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March 2024 in “Experimental Dermatology” This review discusses recent findings on fibrotic lipodystrophy, highlighting the critical roles of lipid-filled cells in tissue function and their loss during fibrogenesis, with implications for fibrosis in tissues like skin, lung, and liver.
6 citations
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October 1983 in “PubMed” This study found no significant protective effect of coenzyme Q10 on hair loss from anthracycline antibiotics, although liver enzyme elevations were less frequent with CoQ10.
5 citations
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May 2020 in “Clinical Phytoscience” In this study, methanol extract of Cuscuta reflexa leaves significantly reduced blood glucose and improved insulin and liver function in alloxan-induced diabetic rats, indicating potential as an antidiabetic and organ-protective agent.
5 citations
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December 2015 in “Asian pacific Journal of Tropical Biomedicine” In this study, the aqueous extract from Phthirusa pyrifolia leaves significantly decreased testosterone levels in male Wistar rats without causing liver or kidney damage, suggesting potential effects on libido and reproduction.
4 citations
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December 2020 in “Dermatologic Therapy” This study reports a case of Ellis van Creveld syndrome in a 40-year-old Iranian woman, highlighting uncommon features such as pectus excavatum, Phrygian cap gallbladder, liver hemangioma, polycystic ovarian disease, and breast fibrocystic cysts.
4 citations
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October 2020 in “Therapeutic drug monitoring” In this study, researchers found that targeting a tacrolimus trough level of 4–7 ng/mL after liver transplantation resulted in comparable graft and patient survival rates to higher levels, while improving liver and kidney function markers.
4 citations
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July 1948 in “Experimental biology and medicine” This study found that continuous extraction of crude casein with hot ethanol reduced its nutritive quality and growth rates in rats, although liver supplementation restored normal growth.
2 citations
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February 2016 in “African Journal of Traditional Complementary and Alternative Medicines” In this study, prolonged ingestion of linseed in rabbits was observed to be safe, showing no significant weight gain or anatomical anomalies in liver and kidney biopsies.
2 citations
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January 2009 in “Journal of Oleo Science” In this study, while young rats fed a commercial standard diet with possibly deteriorated oil showed normal growth, they also exhibited liver surface changes and altered serum lipid levels compared to those on a defined diet.
2 citations
,
January 2008 in “Elsevier eBooks” This chapter discusses the concepts of regeneration and homeostasis, noting that in vertebrates, regeneration is limited to certain tissues like liver, blood, and bone.
2 citations
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June 1985 in “PubMed” This study observed that ethylenthiourea's lethality increases with dose accumulation and ethanol co-administration, while impaired liver function and various adverse effects were noted in long-term treated rats.
1 citations
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October 2024 in “World Journal of Gastroenterology” This article critiques Huang et al. while emphasizing the critical role of the Wnt signaling pathway and M2 tumor-associated macrophages in liver cancer progression, and suggests targeting the Wnt pathway could offer therapeutic benefits.
1 citations
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October 2023 in “Journal of the Endocrine Society” This case presentation reported worsening hyperglycemia in a diabetic male patient after starting finasteride, suggesting that 5-alpha reductase inhibitors may induce hyperglycemia through insulin resistance and liver disturbances in some individuals.
1 citations
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December 2021 in “Animals” This study concluded that thyroid atrophy, alopecia, and hyperkeratosis in sheep are associated with deficiencies in selenium and zinc in serum and liver.
1 citations
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April 2020 in “Journal of Mind and Medical Sciences” This case report discusses a 56-year-old female patient with multiple risk factors, including diabetes mellitus and liver cirrhosis, who developed necrotizing fasciitis, emphasizing the complexity and high cost of treatment required.
1 citations
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April 2019 in “Reumatología Clínica (English Edition)” In this systematic review and meta-analysis, researchers found that methotrexate and leflunomide have similar efficacy for rheumatoid arthritis as first-line treatments, but methotrexate offered a greater reduction in swollen joints, while leflunomide was more associated with liver enzyme increases and fewer gastrointestinal side effects.
1 citations
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January 2019 in “International Journal of ChemTech Research” This study reviews the pharmacological properties of the plant Eclipta prostrata, highlighting its potential in treating various conditions including wound healing, diabetes, liver protection, alopecia, gum disease, cancer prevention, bone health, and antimicrobial effects, alongside its traditional use in tropical regions.
1 citations
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January 2014 in “Assiut Veterinary Medical Journal/Maǧallaẗ Asyūṭ al-ṭibiyyaẗ al-baytariyyaẗ” This study in Aswan governorate reported that emaciated cattle showed decreased blood cell counts and serum minerals, as well as elevated liver enzymes, possibly associated with parasitic infections.
June 2026 in “International Journal of Ayurvedic Medicine” This randomized clinical trial observed that Facia Men’s capsule significantly reduced hair shedding in men with androgenetic alopecia over 12 weeks without affecting renal or liver function, though a small change in blood glucose suggests monitoring metabolic health.
June 2026 in “International Journal of Ayurvedic Medicine (Hyderabad)” This study found that Facia Men’s capsule significantly reduced hair shedding in men with androgenetic alopecia over 12 weeks, without notable renal or liver safety concerns.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research highlights the various traditional uses of E. alba (bhringraj), noting its benefits for hair growth, liver function, and skin conditions such as eczema and pruritis, though results are not reported in this abstract.