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Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Mutations in certain receptors can cause diseases and offer new treatment options.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Ozone therapy might improve cancer treatment and reduce its side effects.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The hair keratin gene KRT81 is found in both normal and breast cancer cells and helps them invade surrounding tissues.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.