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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Different types of skin cells play specific roles in development, healing, and cancer.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Finasteride safely lowers DHT levels without affecting testosterone.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Wool follicles are complex, involving interactions between different cell types and structures.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.