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Older people in Kerala often have skin conditions, with dry skin being the most common, and certain skin issues are linked to high cholesterol and diabetes.

Skin aging reflects overall body aging and can indicate internal health conditions.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Men with early hair loss may have higher insulin resistance and should be checked for related health issues.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Microneedles help treat hair loss by improving hair surroundings and promoting growth.

Finasteride safely reduces excessive hair growth in women.

Certain transporters are found in human hair follicles and may affect hair growth and loss.

Niosomes are a promising and effective way to deliver drugs through the skin.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Granules improve hair loss treatment by targeting follicles.

The study concluded that the most common skin changes in elderly people are wrinkles and dry skin, with various infections, benign tumors, and changes in nails and hair also being significant.

Adequate vitamin D might lower, and high hair chromium might increase DNA damage in obese women.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

PSA can help diagnose high androgen levels in women.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

High-fructose diets can cause irreversible kidney damage.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.